LymeRICK - Lyme borreliosis and Related Infections Centre of Knowledge

A bacterial cytokine (micrococcus luteum - bacterial pheromone) (PDF)
Mukamolova GV et al. PNAS 1998; 95:8916-8921. Viable cells of Micrococcus luteus secrete a factor, which promotes the resuscitation and growth of dormant, nongrowing cells of the same organism. The resuscitationpromoting factor (Rpf) is a protein, which has been purified to homogeneity. In picomolar concentrations, it increases the viable cell count of dormant M. luteus cultures at least 100-fold and can also stimulate the growth of viable cells. Rpf also stimulates the growth of several other high G1C Gram-positive organisms, including Mycobacterium avium, Mycobacterium bovis (BCG), Mycobacterium kansasii, Mycobacterium smegmatis, and Mycobacterium tuberculosis. .... This report is thus a description of a proteinaceous autocrine or paracrine bacterial growth factor or cytokine. COULD RPF also awaken other dormant microbes? - could co-infection with micrococci be a relevant factor promoting growth of and recurrence of symptoms caused by Borrelia burgdorferi?
Date Added: 14.12.06	Visits: 2339

CHRONIC FATIGUE SYNDROME IN HORSES: DIAGNOSIS AND TREATMENT OF 4 CASES
Tarello W. Comp Immunol Microbiol Infect Dis 2001 Jan;24(1):57-70. Pictures of blood smears contain cocci, but also in RBCs a few piroplasma incl. a ring-form ?
Date Added: 15.12.06	Visits: 1389

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