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| Links: Piroplasma & other "ringforms" |
| Investigation of transfusion transmission of a WA1-type ... |
Investigation of transfusion transmission of a WA1-type babesial parasite to a premature infant in California
Kjemtrup AM et al. Transfusion. 2002 Nov;42(11):1482-7.
A premature infant in California developed respiratory distress associated with infection with a protozoal parasite, Babesia. The infant had received two blood transfusions, one from the father and one from an anonymous donor (Donor A). This study describes the follow-up required to identify the source and species of Babesia that infected the infant. .. Samples were tested using blood smear examination, serology, PCR, and hamster inoculation. Identity of the recovered Babesia parasites was confirmed by DNA amplification by PCR, genetic sequencing of the 18S gene, and phylogenetic analysis. .. WA1-type Babesia was recovered from the infant. Neither parent was the source of infection. Serology and hamster inoculation confirmed WA1-type Babesia infection in Donor A. |
| Date Added: 17.12.06 |
Visits: 1649 |
| Life-threatening babesiosis in a women from Wisconsin |
Iacopino V, Earnhart T. Arch Intern Med. 1990 Jul;150(7):1527-8.
A 63-year-old women from Wisconsin presented with severe hemolytic anemia and was found to have babesiosis by red blood cell morphologic appearance and serologic testing. Despite having an intact spleen, she developed adult respiratory distress syndrome, which required prolonged mechanical ventilation. An unusually high level of parasitemia was noted and resolved completely following treatment with quinine, clindamycin, and exchange transfusion.
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| Date Added: 17.12.06 |
Visits: 1445 |
| Molecular evidence of coinfection of Borrelia .. HGE & Babesia ... |
Molecular evidence of coinfection of Borrelia burgdorferi sensu lato, human granulocytic ehrlichiosis agent, and Babesia microti
Skotarczak B et al. J Parasitol. 2003 Feb;89(1):194-6.
Of the 533 processed ticks, 16.7% were positive for B. burgdorferi s. l., 13.3% for B. microti, and 4.5% for the HGE agent. Twenty ticks were coinfected with 2 or 3 of the pathogens. |
| Date Added: 17.12.06 |
Visits: 1408 |
| Neurologic complications following the treatment of human Babesia microti infection ... |
Neurologic complications following the treatment of human Babesia microti infection with diminazene aceturate
Ruebush TK 2d et al. Am J Trop Med Hyg 1979 Mar;28(2):184-9.
After his recovery from babesiosis, the patient developed acute idiopathic polyneuritis (Landry-Guillain-Barre Syndrome), which was probably related to his diminazene therapy." .. OR TO UNRECOGNIZED CONCURRENT BORRELIOSIS? |
| Date Added: 17.12.06 |
Visits: 1411 |
| Ocular findings in human babesiosis (Nantucket fever) |
Ortiz JM, Eagle RC Jr. Am J Ophthalmol. 1982 Mar;93(3):307-11.
The retinopathy was probably the result of focal vasculitis secondary to immune complex disease caused by chronic infection.
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| Date Added: 17.12.06 |
Visits: 1607 |
| Persistent parasitemia after acute babesiosis |
Krause PJ et al. N Engl J Med 1998 Jul 16;339(3):160-5.
The experience of one initially asymptomatic subject is instructive. Bab. microti DNA was amplified from his blood during the 5th and 17th months after parasites were first detected. He then had his first apparent episode of babesial illness and was hospitalized with 3 percent parasitemia. He was febrile and had rigors, sweats, anorexia, nausea, and stupor. During hospitalization, a primary intracapsular renal tumor was identified. After a standard one-week course of clindamycin and quinine therapy, he became asymptomatic and microscopically detectable parasites disappeared from his blood. Parasites were discovered once again, however, in about 1 percent of his erythrocytes 6 weeks later (27 months after the initial parasitemia), when the affected kidney had been scheduled for removal. Therapy with clindamycin and quinine was reinstituted for another week. One week, three months, and one year after surgery, neither microscopy nor DNA amplification revealed babesial parasites. This experience indicates that babesial infection may recrudesce after many months of asymptomatic parasitemia and that, although a standard course of clindamycin and quinine therapy usually is effective, it may fail. PDF |
| Date Added: 17.12.06 |
Visits: 5326 |
| Relative bradycardia and lymphopenia in patients with babesiosis |
| Kim N, Rosenbaum GS, Cunha BA. Clin Infect Dis. 1998 May;26(5):1218-9. "medical records of 17 patients with babesiosis were reviewed. Nine of 17 patients (52.9%) presented with fever (temperature, > 101 degrees F (~38.3oC), and 8 of the 9 patients (88.9%) had relative bradycardia. Four of the nine patients (44.4%) had morning temperature spikes during initial hospitalization. As revealed by laboratory analysis, 13 of 17 patients (76.5%) with babesiosis had lymphopenia, and 5 of 17 patients (29.4%) had rouleaux formation in their peripheral blood smears. |
| Date Added: 17.12.06 |
Visits: 1623 |
| Retrospective seroepidemiological survey for human babesiosis in an area in Japan ... |
Retrospective seroepidemiological survey for human babesiosis in an area in Japan where a tick-borne disease is endemic
Arai S et al. J Vet Med Sci. 2003 Mar;65(3):335-40. "In addition, four sera showed an IFAT titer of 1:100 against the U.S. type, but they appeared to be false-positive because they were cross-reactive against the Hobetsu and Kobe types, and also because a U.S.-type parasite has not been found in Japan. Our results suggest that human babesiosis in Japan occurred prior to the discovery of the index case in 1999 and that the infections were caused mainly by Hobetsu-type parasites. PDF
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| Date Added: 17.12.06 |
Visits: 1226 |
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